Welcome to The Chaturvedi Lab
Systems, Synthetic & Quantitative Virology Lab
We Study Design Principles in Virology to Engineer the Future of Medicine
We decipher genetic circuits pivotal in determining viral fates. Our mission not only pivots on understanding the architecture of the fate-dictating genetic circuits, but leverages these design principles to engineer indomitable therapies — therapies envisioned to outsmart viral evolution with a towering genetic barrier. With a particular intrigue in the shadowy realm of latency, oncogenesis, developmental disorders associated with DNA viruses, the transmission mechanics of pandemic potential RNA viruses, we dive deep, exploring, understanding, and innovating to make the next-generation medicine and help human health.
Latest Publications
Disrupting autorepression circuitry generates “open-loop lethality” to yield escape-resistant antiviral agents
Chaturvedi* et al. Cell 2022
(*co-corresponding author)
Interference with viral negative feedback loops results in overexpression of cytotoxic viral proteins and host cell death, presenting an approach to antiviral therapy with a high barrier to the evolution of resistance.
Our Collaborators
At Chaturvedi Lab, we are united by a collaborative spirit, ensuring every discovery in our pursuit of viral design principles represents a shared step towards a healthier future. If your project resonates with our mission, we welcome you to join our journey of innovation and discovery by collaborating with our diverse team.
Few of our collaborators:
